Which foods should not be consumed during the diet?1. Histamine Rich Foods Histamine levels are high in long-stored or ripening foods.Fermented alcoholic beverages, especially wine, champagne and beerFermented foods: pickles, vinegar, mayonnaise, soya sauceProcessed meats: salami, sausage, bacon, sausageDried fruits: apricots, plums, figs, grapes, mulberries, dried fruits and pulpsCitrus fruitsAged cheeses including goat cheeseSome nuts (such as walnuts, cashews, peanuts)AvocadoSmoked fish and some varieties of fish: mackerel, tuna, anchovies, sardines 2. Histamine TriggersIn addition, certain foods cause the release of histamine in the small intestine. These foods are called histamine releasers.Alcoholic drinksCheese, fondueChocolateCow milkSome vegetables (tomatoes, spinach, aubergines, aubergines, potatoes)Some fruits (papaya, pineapple, banana, strawberry, kiwi)Shellfish, fish saucesWheat germMost food additives and food colourings 3. Foods that Block DAO EnzymeAlcoholEnergy drinksBlack teaMate teaGreen Tea 4. Foods that are both high in histamine and block the DAO enzyme:Alcoholic products (beer, wine, champagne)Free FoodsMangoPearWatermelonMelonAppleGrapeBlackberryApricotPlumRokaBeetrootAsparagusBroccoliBrussels sproutsCarrotCauliflowerGarlicLettuceOnionGarlicQuinoaBuckwheatRiceFresh meatsPeasLentilMint, Thyme, Sage, RosemaryTurmericGingerCoconut milk/oilAlmond milkCoconutStinging nettleSweet potatoEgg (controlled)Fresh big fishChestnutHerbal and fruit teasOlive/olive oilGheeSesameHow often should foods be added during reintroduction?All eliminated foods should not be included at the same time. When adding, it should be started with foods that are thought not to harm the person. Foods should be given to the body little by little.In the reintroduction phase, the selected food should be introduced for one day and waited for three days. If the body reacts after the banned food is tried, the transition period to another banned food should be at least one week. If the body does not react, another banned food can be introduced after three days.During the reintroduction phase, a food diary can be kept to identify foods that cause a reaction. This makes it easier both to check the findings and to act according to the results.

Histamine Intolerance: All You Need to Know

Histamine is a product of the breakdown of histidine, an amino acid that participates in many reactions in the body. When histamine, which acts as a neurotransmitter in the immune and digestive system, cannot be eliminated from the body quickly enough and &#x27;histamine intolerance&#x27; develops. Histamine intolerance occurs when the histamine taken into the body cannot be broken down and accumulates in the body and causes allergic reactions in people.This condition usually develops when the DAO enzyme is deficient. This enzyme is the main enzyme responsible for the breakdown of histamine and determines the rate of histamine breakdown. When the DAO enzyme is insufficient and the body cannot break down histamine, health problems begin to appear in the person. Physical reactions may be exacerbated if the diet is high in histamine or rich in foods that cause histamine release. Although the symptoms are similar to allergies, unlike allergies, they are long-lasting and do not appear suddenly. It is also very difficult to diagnose with blood and allergy tests.Symptoms of Histamine Intolerance:DizzinessFatigueHeadacheFlushing, especially of the head and chestNasal congestion, difficulty breathingConstantly runny or itchy noseHerpesFrequent sneezingItchingDry or scaly skinAtopic dermatitisDigestive problems (stomach cramps, nausea, vomiting, heartburn, indigestion, gas, constipation and diarrhea)Heart palpitationsTinnitusRed itchy or watery eyesMenstrual irregularityIrritabilityAnxiety What are the Causes of Histamine Intolerance?-Genetically, some people produce less of the enzymes involved in the breakdown of histamine.-Inflammation of the intestinal lining can disrupt the release of the DAO enzyme. Histamine is therefore broken down more slowly.-If inflammation causes the intestinal lining to become permeable, food sensitivities can develop, which can lead to histamine release.-Certain types of bacteria, which are usually present in a healthy intestine, not only reduce histamine release but also reduce the sensitivity of histamine receptors, lowering their activity. In the presence of SIBO, bacteria that are normally found in the colon pass into the small intestine, which can cause excessive histamine release.-Chronic stress and irregular sleep promote high histamine levels.-Some medical drugs such as aspirin increase histamine release.-High levels of ongoing stress and irregular sleep cause high histamine levels.Certain nutrients are needed for histamine-degrading enzymes to work. These include magnesium, vitamin B6 and vitamin C. How Is Conventional Treatment of Histamine Intolerance Performed? Anti-histamine drugs are designed to reduce the effects of histamine by preventing it from binding to histamine receptors. However, these drugs do not reduce histamine levels, they only block its effect.What is the Histamine Diet, How is it done? The main purpose of the histamine diet is to balance its release in the body by eliminating histamine-rich foods for a while. A low histamine diet should be done for 2-4 weeks to eliminate symptoms. The duration of the diet varies according to the symptoms in the body. With the calming of the symptoms, the foods removed from the diet are reintroduced to the body. This period is called &#x27;reintroduction period’.

The relationship between blood glucose levels and mood is bi-directional. While blood sugar can affect mood, a person&#x27;s mood can also affect blood sugar levels. Some studies show that mood and stress can cause fluctuations in blood sugar levels. This is because under stressful conditions, cortisol supplies glucose to the body by utilising protein stores through gluconeogenesis in the liver. This energy helps the person to fight or escape from any stressor. However, in the long term, high cortisol constantly produces glucose, causing blood sugar levels to rise. Maintaining balance in this bi-directional relationship helps to improve both one&#x27;s physical and mental health, as well as the quality of the relationships one builds. Knowing the possible symptoms that may develop in blood sugar fluctuations can help both the person and those around them to better manage the situation in the management of these symptoms.

Effects of Diabetes on Mental Health

Diabetes is a metabolic disease that affects mental health as well as physical health. Changes in blood sugar can directly affect mood. Having hyperglycaemia or hypoglycaemia attacks may affect the person&#x27;s thoughts and all areas of his/her life. This situation may cause stress in the person and may also reflect negatively on social relations. Knowing that diabetes has such effects can help the person to establish healthier relationships with themselves and the people around them.High blood sugar can affect mood as follows:<ul><li>Concentration difficulty</li><li>Tension and anxiety</li><li>Fatigue or low energy</li></ul>At the same time, the body may release adrenaline to stabilise blood sugar. This activates the body&#x27;s fight-or-flight response. This can lead to the following symptoms:<ul><li>Dizziness</li><li>Visual disturbances</li><li>High awareness</li><li>Restlessness</li><li>Irritability</li></ul>Symptoms of low blood sugar that can affect mood are as follows:<ul><li>Irritability</li><li>Feelings of anxiety</li><li>Confusion</li><li>Coordination, concentration and decision-making difficulties</li><li>Aggression and impatience</li><li>Personality and behaviour changes</li></ul>

What are the Procedures Applied in Smile Makeover? In smile makeover, treatment is usually applied to the upper and lower eight or ten teeth. The most commonly used treatments include multiple porcelain veneers; because they are both conservative restorations and provide a highly aesthetic appearance. Porcelain crowns, bridges, implants, and even implant-supported dentures can also be part of smile design, depending on the individual&#x27;s needs.How Long Does the Smile Makeover Process Take?The treatment period may take 2-15 days depending on the oral and dental structure and needs of the person.

Smile Design: Redesign Your Smile

Your oral and dental health is of great importance for your aesthetic appearance and self-confidence as well as your general health integrity. If you are not satisfied with your smile, if you are worried about the appearance of your teeth while laughing and if you hide your teeth, you can consider having a smile makeover as a solution to all these problems. In this way, you can have the aesthetic smile and appearance you desire in a short time, and at the same time you can experience an increase in self-confidence.What is a Smile Makeover?Smile makeover is a process in which the undesired appearance is improved through one or more cosmetic dentistry procedures. Personalised treatment plans include all health and aesthetic-oriented procedures. Anyone who wants to change their appearance or has problems with their teeth can consider having this treatment. In this procedure; <ul><li>Tooth decays are treated</li><li>Crooked teeth are aligned</li><li>Gaps between teeth are closed</li><li>Protrusions are reduced</li><li>Deformities in the gums are corrected</li><li>The length and shape of the teeth are changed</li><li>Prosthesis or implant is placed instead of missing teeth</li><li>Teeth whitening</li><li>Lip contours are shaped</li></ul>or any combination of the above-mentioned can be planned.

It also suppresses stress hormones like cortisol. These effects are associated with better mood, less physical pain, lower blood pressure, a stronger immune system, lower stress levels and depression rates. Positive psychology considers the tendency to laugh and the sense of humor to be one of the 24 fundamental strengths a person can have.Moreover, laughing with other people increases social connectedness and bonds, as well as strengthens relationships. At the same time, it makes the person feel more comfortable by improving the sense of security and safety.Many researchers state that the body cannot distinguish between fake (simulated) or real (spontaneous) laughter. This indicates that you can benefit even by forcing yourself to laugh.

Laughing Protects Your Body and Mental Health

Laughing changes the activity of hormones such as endorphins, dopamine and serotonin. When you laugh, your intake of oxygen-rich air increases, your heart, lungs and muscles are stimulated, which increases the endorphins released by your brain. Being a natural pain reliever, this hormone helps you experience less physical pain, feel better and enjoy life more.From Lynn University in Florida, Dr. According to Matt Bellace, laughter releases the neurotransmitter dopamine, which acts as a reward for the brain, creates a sense of euphoria and plays a crucial role in your motivation to continue the behavior.Laughter also has a similar effect to antidepressants. Laughing activates the release of the neurotransmitter serotonin, the same brain chemical that is affected by SSRIs, the most common types of antidepressants.

Foods Rich in Trans FatsTrans fats are a type of unsaturated fat that can have a detrimental effect on brain health. Trans fats are found naturally in animal products such as meat and dairy products, and they are not a major concern. The problem here is industrially produced trans fats, also known as hydrogenated vegetable oils.These artificial trans fats can be found in shortening, margarine, cream, snack foods, ready-made cakes and prepackaged cookies.Studies show that when people consume higher amounts of trans fats, they have an increased risk of Alzheimer&#x27;s disease, poorer memory, lower brain volume and cognitive decline.It also has negative effects on many other aspects of health, including heart health and inflammation.In a study of 38 women, those who consumed more saturated fat than unsaturated fat performed worse in memory and recognition function.It is known that a diet rich in omega-3 fatty acids protects against cognitive decline. Omega-3s increase the secretion of anti-inflammatory compounds in the brain and have a protective effect, especially in older adults. You can increase the amount of omega-3 fats in your diet by eating foods such as fish, chia seeds, flax seeds and walnuts.Processed FoodsHighly processed foods are high in sugar, added fats and salt. It includes foods such as chips, smoothies, instant noodles, microwaveable popcorn, grocery store sauces, and ready meals. These foods are generally high in calories and low in nutrients. These are foods that cause weight gain and negatively affect brain health.The nutritional composition of processed foods in the Western diet may adversely affect the brain, contributing to the development of degenerative diseases.A study involving 18,080 people found that a diet rich in fried foods and processed meats was associated with lower scores in learning and memory.Animal studies have shown that rats fed a high-fat, sugar-rich diet for eight months developed impaired learning ability and adverse changes in brain plasticity. Another study found disruptions in the blood-brain barrier in rats fed a high-calorie diet.One of the ways that processed foods negatively affect the brain is by reducing the production of a molecule called brain-derived neurotrophic factor (BDNF). This molecule is found in various parts of the brain, including the hippocampus, and is important for long-term memory, learning, and the growth of new neurons. Therefore, any reduction can have negative effects on these functions.Therefore, it is beneficial to stay away from ready-made and processed foods and to consume healthy and natural foods instead.AlcoholChronic alcohol use causes a decrease in brain volume, metabolic changes, and a breakdown of neurotransmitters, the chemicals the brain uses to communicate.Excessive alcohol consumption can also have adverse effects in non-alcoholics.One-off episodes of heavy drinking are known as &quot;binge drinking.&quot; This can cause the brain to interpret emotional cues differently than normal. For example, people are less sensitive to sad faces and more sensitive to angry faces. These changes in emotion recognition are thought to be a cause of alcohol-induced aggression.Also, alcohol consumption during pregnancy can have devastating effects on the fetus. Given that the brain is still developing, the toxic effects of alcohol can cause developmental disorders such as fetal alcohol syndrome.Alcohol use in teenagers is risky because the brain is still developing. Abnormalities in brain structure, function, and behavior have been observed in young people who drink alcohol (compared to non-drinkers).Another negative effect of alcohol is that it disrupts sleep patterns. Drinking large amounts of alcohol before bed reduces the quality of sleep.In short, you should avoid excessive alcohol consumption, especially if you are a teenager or young adult. If you are pregnant, it is best to avoid alcohol altogether.

These Foods Put Your Brain Health in Danger

Your brain is the most important organ in your body. It makes your heart beat, your lungs breathe, and all systems in your body work. For this reason, it is very important to keep your brain working at an ideal level with healthy eating habits.Some foods have negative effects on your brain. It affects your memory, mood and increases your risk of dementia. However, you can help reduce the risk of disease by eliminating certain foods from your diet.List of foods you should exclude from your diet:Sugary DrinksSugary drinks; includes beverages such as fruit sodas, sports drinks, energy drinks, and juice.Consuming sugary drinks too often not only increases your waist circumference, type 2 diabetes and heart disease risk, but also has negative effects on your brain.Excessive consumption of sugary drinks increases the likelihood of developing type 2 diabetes, which has been shown to increase the risk of Alzheimer&#x27;s disease. In addition, high blood sugar levels can increase the risk of dementia, even in people who do not have diabetes.The primary ingredient in many sugary drinks is high fructose corn syrup, which consists of 55% fructose and 45% glucose.High fructose intake can lead to obesity, high blood pressure, high blood fats, diabetes and arterial dysfunction. These aspects of the metabolic syndrome can lead to an increased risk of developing dementia in the long term.Among the alternatives that can be preferred instead of sugary drinks; water, unsweetened iced tea, herbal teas, vegetable juice, and plant-based dairy products.Refined CarbsRefined carbohydrates include sugars and highly processed grains such as white flour.These types of carbohydrates usually have a high glycemic index (GI). This means your body digests them quickly, causing a spike in your blood sugar and insulin levels. Also, when consumed in larger quantities, these foods often have a high glycemic load (GL). GL refers to how much a food raises your blood sugar levels, depending on the serving size.Foods with high GI and high GL have been shown to impair brain function. Studies have shown that even a single meal with a high glycemic load can impair memory in both children and adults.Therefore, low GI carbohydrates, vegetables, fruits, legumes and seeds should be preferred in the daily diet.

So, what are the things that negatively affect the circadian rhythm?Having an irregular sleep schedule: The body likes consistency when it comes to sleep. If you go to bed and wake up at different times each day, your circadian rhythm and subsequently your energy levels will be negatively affected.Use of electronic devices late at night: The use of electronic devices and bright light, especially before sleep, suppresses melatonin and disrupts your circadian rhythm.Being stressed: Stress activates the sympathetic nervous system (fight or flight), which causes the release of the stress hormone cortisol. High cortisol levels at bedtime can disrupt your body&#x27;s internal clock, causing you to stay awake.Presence of dysbiosis: Dysbiosis is the name given to the imbalance that develops in the ratio of beneficial and harmful bacteria in the intestines. This imbalance increases inflammation in the body and is the root cause of many diseases. In addition, it can significantly reduce sleep quality. Studies have shown that sleep apnea, insomnia, and narcolepsy are linked to certain imbalances in the microbiome.Lack of exercise: Sleep and exercise have a bidirectional relationship. Exercise improves sleep quality, while quality sleep improves physical performance. Conversely, however, lack of exercise can negatively affect sleep, and insufficient sleep can reduce physical performance. In order for you to sleep better at night, your body must be tired during the day and have lost a certain amount of energy. When you don&#x27;t have a regular exercise routine, you are likely to experience sleep problems.Eating large meals before bedtime: Eating larger meals earlier in the day and choosing smaller meals late at night are known to improve sleep quality. It is very important that the feeding ends 3-4 hours before going to sleep and that the body has now done the digestion work.

Circadian Rhythm and Factors Affecting Rhythm Negatively

The circadian rhythm is your internal clock that determines when you wake up, when you sleep, and how your energy fluctuates throughout the day. Just as there are things you can do to support your body&#x27;s internal clock, you may be doing or experiencing things that cause it to malfunction.

Vitamin D also plays a role in the formation of sex hormones. A woman who does not have enough vitamin D in her body may not have a healthy response to estrogen, even if her healthy ovaries and circulating hormonal levels are normal.As can be understood from all this, vitamin D plays a very important role in our overall health. Therefore, it is important to meet our daily needs. It is beneficial to sunbathe in a safe amount in summer and to use vitamin D supplements in winter. It takes some time for vitamin D to be synthesized in the skin. To speed up the process, you can apply some olive oil or a thin layer of sesame oil to your body. In order to increase the absorption of supplements, you should definitely consume fatty foods beforehand.

Benefits of Getting Sunlight and Vitamin D

Exposure to sunlight in daily routine is essential for living a healthy life. According to a new study, sunlight increases the production of nitric oxide, which helps dilate blood vessels and improve their flow.It also provides sunlight to the internal setup of our biological rhythm. Our pineal gland needs bright sunlight during the day and darkness in the evening to produce melatonin. Therefore, our rhythm of light and dark during the day directly affects our sleep quality. Melatonin production is not just a determinant of the sleep cycle. It is also of great importance for the ovaries and fertility. It also determines mood and energy level by influencing many other cellular and hormonal functions. Perhaps most importantly, sunlight reacts with the skin to produce vitamin D, which reduces the risk of many diseases such as heart attack, diabetes and multiple sclerosis. It stimulates the pancreas to produce insulin, improves dental health, regulates muscle tone, relieves headaches and strengthens the immune system. Active vitamin D is one of the most potent cancer cell inhibitors. It provides protection against cancer by preventing out-of-control cell division. This makes it a protective shield against all types of cancer, including melanoma.

What are the Types of Dysbiosis? There are three types of dysbiosis. In most cases, you can have all three types. This is not a rare condition. The types of dysbiosis are as follows:<ul><li>Type 1. This type of dysbiosis occurs when the number of beneficial bacteria in your intestines decreases.</li><li>Type 2. It develops when there is too much growth of harmful bacteria in your stomach.</li><li>Type 3. It occurs when you lose your microbiome diversity. This means that you lose both good and bad bacteria in your stomach.</li></ul>Research shows that you may be more likely to have stomach problems when your gut microbiome is out of balance. At the same time, studies have also shown that dysbiosis is linked to IBD. For all these reasons, improving the gut should be at the top of the action plan in the treatment of both intestinal diseases and chronic diseases.

What is Gut Dysbiosis?

The intestines contain trillions of microorganisms that compose the gut microbiome. This intestinal flora consisting of bacteria, fungi and viruses directly affects our health. Bacteria in the gastrointestinal system; They are divided into two as beneficial bacteria and harmful bacteria. Beneficial bacteria help digest what we eat, produce vitamins, keep inflammation in balance, detoxify toxins, produce energy for intestinal cells, regulate cholesterol metabolism, maintain ideal PH balance, strengthen immune function and many more. Harmful bacteria, on the other hand, produce toxins and starch fermentation that cause bloating and gas formation. These bacteria tend to travel to different parts of the intestines and move to other places, such as the stomach and small intestine. When the number of harmful bacteria increases (when you use too many antibiotics, do not consume fibre-containing foods and consume too much sugar, which is one of the food sources of harmful bacteria), this balance is disturbed. This imbalance in the intestine is called &#x27;dysbiosis&#x27;. In the presence of dysbiosis, we become vulnerable to many diseases. When the intestinal microbiome loses bacterial diversity, the risk of developing a chronic disease increases. In addition, the decrease in intestinal bacteria with age can contribute to the development of dysbiosis. Dysbiosis interferes with healthy immune system activity in several different ways. Harmful bacteria produce many harmful toxins, including lipopolysaccharides (LPS toxins). Both the bad bacteria and these toxic by-products disrupt the structure of the protective lining inside the intestines. The job of the intestinal lining is to keep pathogens and toxins safely locked away in the gut while allowing nutrients to enter the bloodstream. But when bad bacteria, LPS toxins and other harmful compounds attack, the intestinal barrier is damaged and these compounds enter the bloodstream. From there they can reach any part of your body and pose a serious threat to your health. Your immune system recognises these threats and starts to mount a response. It uses inflammation as one of its main defence tools. If new threats are constantly leaking through the intestinal barrier, your immune system cannot stop its response. This leads to systemic and prolonged inflammation, which is the root cause of many autoimmune and chronic conditions.

Are You at Risk? There are a number of known risk factors for both pre-diabetes and type 2 diabetes. If you have one or more of the following risk factors, you should consult a specialist immediately:<ul><li>Being overweight or obese (BMI 25 or higher)</li><li>Sedentary lifestyle</li><li>Family history of diabetes (especially first-degree relatives)</li><li>Low HDL or good cholesterol (less than 35 mg/dl or 0.9 mmol/l) and high triglycerides (more than 250 mg/dl)</li><li>High blood pressure (sustained 140/90 mmHG or higher)</li><li>History of cardiovascular disease</li><li>History of gestational diabetes</li><li>Diagnosis of polycystic ovary syndrome (PCOS)</li><li>Giving birth to a baby weighing more than 4 kg</li><li>Previous haemoglobin A1c test result of 5.7 or higher </li></ul>What are the Precautions to be Taken?Changing nutrition and lifestyle habits is the most important step to be taken in the treatment of diabetes. With the changes being made, the development and progression of diabetes can be stopped or even reversed. Nutrition and lifestyle changes include:<ul><li>Personalised nutrition plan</li><li>Being active</li><li>Losing weight</li><li>Avoiding long periods of inactivity</li><li>Getting enough sleep</li><li>To apply stress management techniques</li></ul>

The Epidemic of Our Age: Type 2 Diabetes

Today, type 2 diabetes has become an epidemic. It is estimated that more than 500 million adults worldwide suffer from diabetes. And this number is increasing day by day. But pre-diabetes (hidden diabetes) is a much more common problem than full-blown diabetes. It occurs when blood sugar starts to rise and indicates that the amount of insulin produced cannot manage blood sugar levels. If no action is taken, this leads to type 2 diabetes. And unfortunately, many people do not even realise they have pre-diabetes. Timely diagnosis of pre-diabetes is important because organ damage occurs in approximately 20 percent of people diagnosed with diabetes. At the same time, various health problems such as visual impairment and risk of heart attack occur.The disease is no longer limited to middle-aged and older adults; children and young people are increasingly being diagnosed with type 2 diabetes. Their risk of developing many other chronic diseases during their lifetime also increases significantly. This is because diabetes is a metabolic disease and affects the whole body negatively. What are the Symptoms of Type 2 Diabetes?It may include one or more of the following:<ul><li>Thirst, dry mouth and frequent urination</li><li>Tingling or burning sensation in the feet, legs, hands or other parts of the body</li><li>Weakness and fatigue</li><li>Blurred vision</li><li>Sudden feeling of hunger</li><li>Sudden attacks of anger and rage</li><li>Increase in body weight</li><li>Frequent or recurrent infections (urinary tract infections, fungal infections)</li><li>Slow healing of cuts and wounds</li></ul>What are the Possible Complications of Type 2 Diabetes?<ul><li>Cardiovascular diseases</li><li>Neuropathy (nerve damage)</li><li>Diabetic nephropathy (permanent kidney damage)</li><li>Retinopathy (eye damage)</li><li>Diabetic foot</li><li>Skin diseases</li><li>Hearing impairment</li><li>Alzheimer&#x27;s disease</li><li>Depression</li></ul>

What are the Factors Causing Leaky Bowel Syndrome?<ul><li>Frequent use of antibiotics</li><li>Experiencing acute emotional or physical trauma</li><li>Chronic stress</li><li>Chronic dysbiosis</li><li>Use of non-steroidal anti-inflammatory drugs, ibuprofen or drugs that act in this way</li><li>Toxins</li><li>Liver toxicity and excess fat consumption</li><li>Alcohol dependence</li></ul>Risk factors for the development of leaky gut include structural/anatomical problems, motility disorders, immunodeficiency, reduced digestive secretions and old age.Which treatment methods should be used?The most effective way to treat this gastrointestinal disorder is to follow the intestinal healing protocol (remove, replace, repair and rebalance). In this, it is important to eliminate foods and factors that damage the intestines and replace them with therapeutic foods. In addition, it is necessary to repair the gut with special supplements such as butyric acid and rebalance the microbiome with probiotics. Other factors that increase treatment success are reducing stress levels, improving sleep quality, and limiting smoking and alcohol consumption.

What is Leaky Bowel Syndrome?

Leaky gut syndrome is a digestive problem that occurs for various reasons. This problem occurs when the tight junctions between the cell layers, which determine what can and cannot enter the bloodstream, are damaged. These junctions are the gateway between the intestines and the bloodstream. Under normal conditions, the tight junctions in the intestine only allow the passage of digested nutrients, minerals and vitamins, but when these junctions are opened, unwanted substances such as toxins, bacteria and undigested food particles also enter the bloodstream. Loosening of this structure is called &#x27;leaky gut syndrome&#x27;. If the immune system does not recognise the various microorganisms and particles that pass into the bloodstream, it can initiate an autoimmune reaction. Recent studies show that almost everyone with autoimmune disease has leaky gut syndrome, with or without symptoms. Leaky gut syndrome can cause various symptoms. It can manifest itself with many symptoms such as food allergies, immune system diseases, skin problems, neurological problems, vitamin deficiencies, untreated depression, chronic headache, fibromyalgia, constipation, diarrhea, irritable bowel syndrome, chronic fatigue. Some people do not experience any digestive symptoms despite the presence of leaky gut. Instead, swelling of the hands and feet after eating, muscle tension and stiffness in the morning, brain fog and distraction when certain foods are consumed.

Of course, these are not the only benefits of cold contact, which supports the immune system. Besides all these; It keeps skin and hair healthy, soothes itchy skin, increases brown adipose tissue, aids weight loss, increases resilience to stress, reduces the effects of depression and increases energy levels. In short, it contributes to the optimal functioning of the body.The ideal way to take a cold shower; at the end of a warm shower is to slowly lower the temperature and cool you down until you start to feel uncomfortable. Then it is to stay under water for 2-3 minutes. Breathing calmly and deeply will help reduce your mental and physical discomfort. You can gradually increase the degree and duration of your cold shower applications over time.However, if you have some health problems, you should avoid taking cold showers. These health problems are listed as follows;<ul><li>Being underweight or having an eating disorder (which can cause a lot of chills)</li><li>Have a delicate heart or respiratory disease that makes it difficult to breathe (check with your doctor first)</li><li>Pregnancy status</li><li>Symptoms of hypothermia (lower than normal body temperature and chills)</li></ul>

Health Benefits of Taking a Shower with Cold Water

It is known that cold water has positive effects on our general health. Its effects on the immune system have also been widely studied. Cold water exposure increases the white blood cell (leukocyte) count as the body is forced to respond to changing conditions. Over time, the body gets better at activating defenses. This means that taking cold showers can help increase resistance to common illnesses such as colds and flu.A 2014 study found that diving into cold water causes the body to release adrenaline. This has two effects: It makes the immune system produce more anti-inflammatory substances. It also reduces the inflammatory response to infections. Both of these effects help the body resist disease.However, cold contact can increase autophagy (the body&#x27;s way of cleaning damaged cells) and apoptosis (programmed cell death) inside the body.A 2007 study showed that cold showers can make the body more resistant to certain types of cancer.

Vitamin C

Boost your immune system

Vitamin C administered intravenously in high doses accumulates in tumor tissue, shows oxidant properties and causes the death of tumor cells. In order for this effect to occur, the level of vitamin c in the blood must reach a certain level. High dose vitamin c application reduces the side effects of treatments such as chemotherapy and radiotherapy and increases the effectiveness. It strengthens the immune system and helps relieve chronic fatigue. 4-6 sessions are recommended at 3-7 day intervals.

A.L.A. (Alpha Lipoic Acid)

Antioxidant power

It is a powerful antioxidant and can recycle other antioxidants such as vitamin C, vitamin E and glutathione. It has anti-inflammatory properties and has been observed to reduce NF-κB activity in TNF-stimulated cells in vitro in a dose-dependent manner. It has a rapid onset of action and improves paresthesia, numbness, sensory deficits and muscle strength in addition to neuropathic pain. 4-6 sessions at 5-7 day intervals are recommended.

Curcumin

Super potent anti-inflammatory support

Curcumin is known as a very powerful anti-inflammatory, antioxidant, anti-diabetic and anti-cancer, reduces oxidative stress, regulates blood pressure and strengthens immunity, facilitates the treatment process of chronic inflammatory diseases and protects against metabolic syndromes. There is some evidence that curcumin has neuroprotective properties. It is thought that it may help prevent or delay the development of neurodegenerative diseases such as Alzheimer's. Some research suggests that curcumin may inhibit the growth of cancer cells and may be effective in fighting cancer. IV test dose of 1 to 10 mg/Kg on the first day. If tolerated two to three times a week, subsequent doses may increase to 40 mg/Kg.

Glutathione

Revitalize your cells

Glutathione is involved in many biological processes such as reducing the damage caused by free radicals, detoxification, cellular redox, vitamin C and vitamin E regeneration and acting as a coenzyme. Provides support to the immune system. It helps to remove heavy metals from the body. It helps to treat many diseases such as diabetes, skin diseases, neurological disorders. 5-10 sessions are recommended at intervals of 3-7 days.

Ozone Therapy

Elevate your well-being

Ozone shows antioxidant effects by fighting free radicals in the body. This helps to reduce cell damage and slow down the aging process. The immunomodulatory effects of ozone stimulate the immune system, providing protection against infections and diseases. IV ozone therapy delivers oxygen directly into the bloodstream and helps tissues utilize oxygen more effectively. Its anti-inflammatory properties can alleviate conditions associated with inflammation.

Holistic Detox Program

Without Accommodation

With Four-Star Ontur Hotel Accommodation

With Five-Star Swissotel Accommodation

A personalized physical, mental, emotional and spiritual cleansing plan

One of the most important problems brought about by the modern lifestyle is the pollution of nature, bodies, emotions and spirit. All of these are interconnected and the solution is a holistic detox. In a holistic detox program, health is addressed not only from a physical perspective, but also from a mental, emotional and spiritual perspective. By creating an effective detox plan, it aims to repair the damage caused by toxins to organs and their functions. In addition, people are taught holistic detoxification disciplines and are provided with detailed information and programs on nutrition and lifestyle habits in order to live a long and healthy life. In a personalized treatment plan, supportive supplements may be prescribed by the needs of a person. Who Can Participate in the Holistic Detox Program? Those who suffer from chronic fatigue, bloating, constipation, indigestion, bad breath, skin problems, sudden increase in appetite, muscle and joint pains, headaches, attention deficit, forgetfulness, sleep disorders, lack of sexual drive, chronic diseases, excessive coffee, alcohol, smoking and drug consumption, stress and environmental pollution. Make an appointment for a free consultation now.

Duration	7 Days	14 Days	21 Days
Without Accommodation	€2000	€3600	€5300
With Four-Star Ontur Hotel Accommodation	€2770	€5140	€7610
With Five-Star Swissotel Accommodation	€3750	€7100	€10550

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